Monday, October 7, 2019
Review the current and potential future treatments for Parkinsons Essay
Review the current and potential future treatments for Parkinsons Disease - Essay Example It is the second most common neurgenerative disorder that affects about 1 million people in America and about 50,000 people in United Kingdom (Jankovic, 2007). The disease is characterized by a gradual loss of the muscular functioning and controlling, resulting in trembling limbs, stiffness and impairment balance. In other words, the disease causes the disorder of movement, motor weakness, spasticity, sensory loss, and cerebellar ataxia (Waters, 2008). It causes slowness of the movement or abnormal involuntary movement (dyskinesia) such as, tremor, chorea, mycolonus, tics and dystopian (Driver-Dunckley et al., 2003). The disease immensely affects sub cortical brain structures (basal ganglia) causing movement disorders. Parkinsonââ¬â¢s disease results from the malfunction and the death of the nerve muscle of the brain cells called neurons. It affects neurons present in the substantia nigra. This part of brain controls the movement and coordination of the body part with the brain (C haudhuri & Tolosa, 2009). Parkinsonââ¬â¢s disease affects substantia nigra, eventually decrease production of dopamine in the brain causing individuals to lose control the movement normally (Olanow & Koller, 1998). Symptoms of Parkinsonââ¬â¢s disease are classified as Primary symptoms that are related to involuntary and voluntary motor functions usually occur on one side of the body. When the symptoms of the Parkinson appear they are mild that eventually progress with the time (Chaudhuri & Tolosa, 2009). According to the study of Waters (2008), by the time the symptoms of Parkinsonââ¬â¢s disease appear, individuals would have already lost about 60 to 80 percent of the dopamine cells (cells that regulate and control the movement). The secondary symptoms appear when the Parkinsonââ¬â¢s disease becomes progressive causing the loss and control of the body movement and damage of brain cell (Waters, 2008). The following is the list of
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